New publication in Radiation Research

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Our recent publication in Radiation Research, “Assessing the Accuracy of Bioluminescence Image-Guided Stereotactic Body Radiation Therapy of Orthotopic Pancreatic Tumors Using a Small Animal Irradiator” is a collaboration between the DaCosta Lab and Dr. Robert Weersink. In this preclincal study, Dr. Sara Rapic (former Post-doctoral fellow) and Timothy Samuel (Ph.D. candidate) demonstrated the improved accuracy of using 3-dimensional bioluminescence…

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The Allan Slaight Breakthrough Fund

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Dr. DaCosta and other scientists discuss the opportunities for scientific breakthrough at PMCC as a result of the historic donation of $50 million in honour of the late Canadian philanthropist, Allan Slaight. Allan Slaight The Princess Margaret Cancer Foundation announced a historic $50 million gift for cancer research in honour of the late Allan Slaight,…

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Welcome new cancer research technician II!

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We would like to welcome a new research technician to our lab: Dr. Emily Chen, MD, Research Technician II Emily was previously part of our lab from 2008-2009, during which she helped to pioneer our first animal window chamber models to study the tumor microenvironment.  In re-joining our lab, Emily will be responsible for conducting…

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Welcome new cancer research technician III!

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We would like to welcome a new research technician to our lab: Michael Edson, MSc., Research Technician III The DaCosta lab is thrilled to have Michael Edson join us in 2022. Michael is an experienced and talented researcher who will help to manage all wet lab operations and preclinical projects.  Michael earned a MSc in…

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Welcome 2021 Summer Students!

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We would like to welcome 5 high school and undergraduate summer students who will be joining the lab this year: Ben Daynes (Aurora High School, Grade 12) Project: Developing health monitoring spectrometer with built-in light source for detection of urine biomarkers. Rachel Jacobson (Wilfred Laurier University, 1st year) Project: Investigating immunotherapy in acute myelogenous leukemia.…

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Dr. DaCosta to Deliver Keynote Presentation at St Michael’s 4th Annual Life Sciences Career Symposium

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The St. Michael’s Hospital Research Student Association’s annual Life Sciences Career Symposium aims to connect trainees to distinguished experts in the Life Sciences. This year’s Symposium will take place on July 9th, 2021, featuring keynote speakers Dr. Samantha Yammine and Dr. Ralph DaCosta. Dr.DaCosta will headline the Biotechnology and Innovation session (1-3PM), sharing his experiences…

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Dr. DaCosta participates in Annual 2021 MBP Career Symposium

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The annual MBP Symposium (which combines the James Lepock Memorial (JLM) Symposium and the annual MBP Alumni Night) is an important MBP event that provides an opportunity for MBP students to present their research in a conference setting. The MBP Symposium fosters scientific debate across disciplines, streams and institutes. MBP students have the opportunity to…

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Dr. Niloufar Khosravi featured on U of T Faculty of Dentistry Website

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Niloufar Khosravi, a DaCosta Lab PhD student alumna was recently featured on U of T’s Faculty of Dentistry site. In the Article, “U of T Researchers Map Regenerative Cells in Implant Wounds” Niloufar summarized her work recently published in Biomaterials.

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Intraoperative Fluorescence Imaging with Aminolevulinic Acid Detects Grossly Occult Breast Cancer: A Phase II Randomized Controlled Trial: Manuscript accepted to Breast Cancer Research

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In 2009, the first patient was enrolled at Princess Margaret Cancer Center in this Phase II randomized controlled trial led by Dr. DaCosta in collaboration with surgeons Drs. Wey Leong and Alexandra Easson and pathologist Dr. Susan Done. The goal was to evaluate the clinical safety, feasibility and diagnostic performance of the PRODIGI handheld fluorescence…

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World’s 1st Patient Surgery in Pivotal Phase III breast cancer trial

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  Today marks an important milestone for SBI Canada’s Phase III RCT entitled “Fluorescence Imaging of Carcinoma During Breast Conserving Surgery”, as the first patient surgery was performed successfully at Orlando Health in Orlando, Florida. (ClinicalTrials.gov Identifier: NCT04815083) This trial utilizes the tumor selectivity of 5-ALA combined with the handheld Eagle fluorescence imaging device to…

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