Members of our lab were pleased to present our research at the inaugural Princess Margaret Hematology Conference (PMHC), held at the Princess Margaret Cancer Centre in collaboration with the International Lymphoma Radiation Oncology Group (ILROG). The PMHC brought together national and international experts in malignant hematology for a two‑and‑a‑half‑day scientific forum focused on advancing research and patient care in hematologic cancers.
The conference featured keynote lectures, plenary and breakout sessions, poster presentations, and networking events aimed at fostering interdisciplinary collaboration among clinicians, basic and translational scientists, and allied health professionals. Scientific discussions spanned leukemia, lymphoma, myeloma, and related disorders, as well as recent advances in allogeneic and autologous hematopoietic stem cell transplantation and immune cellular therapies. A strong emphasis was placed on emerging technologies, precision medicine, immunotherapy, and the development of innovative clinical studies to improve patient outcomes.
Our lab contributed five presentations to the meeting, including two oral presentations and three poster presentations, highlighting our ongoing work and engagement with the broader hematology research community.
Oral Presentations
- Imaging Mass Cytometry to Define Spatial Immune Architecture and Neuro-Immune Signaling in Tumor Microenvironments (Ralph DaCosta)
Authors: Xi Lei, Jennifer Gorman, Dr. Shirley Wang, Dr. Jackson Hartland, Dr. Ralph DaCosta - Capturing the Live Interactions Between T Cells and AML in the Bone Marrow Microenvironment Using Intravital Imaging (Sadaf Mazhab Jafari)
Authors: Sadaf Jafari, Raheleh Niavarani, Xi Lei, Lyndsey DeGuzman, Ralph DaCosta
Poster Presentations
- Utilizing Fluorescence Intravital Imaging to Investigate Bone Marrow Microenvironment Remodeling in Acute Myeloid Leukemia
Authors: Maryam Naimi, Samridhi Bhardwaj, Lyndsey DeGuzman, Sadaf Jafari, Raheleh Niavarani, Xi Lei, Emily Chen, Michael Edson, Ralph DaCosta - Deciphering the Mechanisms Underlying the Pathophysiology and Chemotherapy Resistance in Acute Myeloid Leukemia Using Intravital Imaging and Humanized NSGW41IL7 Mouse
Authors: Raheleh Niavarani, Xi Lei, Sadaf Jafari, Lyndsey DeGuzman, Michael Edson, Shirley Wang, Ralph DaCosta - Redox-Driven Bone Marrow Vascular Remodeling Under Systemic Inflammation: Insights from Intravital Imaging and Sex-Specific Response
Authors: Raheleh Niavarani, Xi Lei, Sadaf Mazhab Jafari, Lyndsay De Guzman, Shirley Wang, Ralph DaCosta
We thank the organizers for creating an outstanding forum for scientific exchange and collaboration, and we enjoyed the opportunity to share our work, receive feedback from experts in the field, and connect with colleagues working to advance the understanding and treatment of hematologic malignancies.
