Research

We develop advanced molecular imaging solutions to improve diagnosis, treatment and monitoring of therapeutic response in cancer and other diseases.

Preclinical

Preclinical Research

The DaCosta research team develops new optical imaging tools, in the fields of intravital microscopy and molecular probes, which are used in specialized animal models of human cancers. These innovative tools enable us to visualize and quantify biological processes and therapy-induced changes in the living tumor. We capture a tumor’s dynamic microenvironment in vivo, over time, at single cell level producing award winning images.

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Clinical Research

The DaCosta lab is focused on bringing innovative solutions to clinical problems with the goal of improving patient care and outcomes. We rely on our clinical partners to frame the problems patients and clinicians experience today and look to offer effective, easily implementable solutions. The DaCosta lab is focused on developing diagnostic, treatment monitoring and guidance imaging tools for use in clinics and operating rooms.

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Clinical Trials

The DaCosta lab has completed over six PI-sponsored medical device clinical trials at UHN and collaborating centers across the Greater Toronto Area. From first-in-human prototype testing, to interventional device trials, our multidisciplinary team has extensive experience moving new devices from our translation research team through clinical testing across multiple indications with a focus on oncology and diabetic wound healing.

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Our Multidisciplinary

Team

Meet the Team
DaCosta Team photo

News

New Publication in Scientific Reports (December 2024)
1030 617 DaCosta Lab

We are pleased to announce a new publication, “Investigating the Effects of…

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Welcome New Postdoctoral Fellow!
259 329 DaCosta Lab

We are very excited to welcome Dr. Raheleh Niavarani as a new…

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New Funding from the Cancer Research Society
1030 229 DaCosta Lab

We are pleased to share that our grant submission to the Cancer…

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Publications

Investigating the Effects of Stereotactic Body Radiation Therapy on Pancreatic Tumor Hypoxia and Microvasculature in an Orthotopic Mouse Model using Intravital Fluorescence Microscopy
1030 617 DaCosta Lab

Our recent paper, “Investigating the Effects of Stereotactic Body Radiation Therapy on…

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Glucagon-like-protein-2 stimulates lacteal contractility and enhances chylomicron transport in the presence of an intact enteric nervous system
1030 417 DaCosta Lab

Our recent paper, ““Glucagon-like-protein-2 stimulates lacteal contractility and enhances chylomicron transport in…

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Collaborations

Academic

Industry

Funding

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