Arcturus Phoon

A handheld device for intra-cavity and ex vivo fluorescence imaging of breast conserving surgery margins with 5-aminolevulinic acid
 1030 678 DaCosta Lab

Our recent paper, “A handheld device for intra-cavity and ex vivo fluorescence imaging of breast conserving surgery margins with 5-aminolevulinic acid,” was published in the Biomedical Engineering Journal (June 2024). Visualization of cancer during breast conserving surgery (BCS) remains challenging; the BCS reoperation rate is reported to be 20-70% of patients. An urgent clinical need exists for real-time intraoperative visualization of breast carcinomas during BCS. We previously demonstrated the ability of a prototype imaging device to identify breast carcinoma in excised surgical specimens administration following 5-aminolevulinic acid (5-ALA) administration. However, this prototype device was not designed to image the surgical…

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Customizable optical tissue phantom platform for characterization of fluorescence imaging device sensitivity
 1030 639 DaCosta Lab

Our recent paper, “Customizable optical tissue phantom platform for characterization of fluorescence imaging device sensitivity,” was published in the Journal of Biomedical Optics (August 2023). Optical tissue phantoms serve as inanimate and stable reference materials used to calibrate, characterize, standardize, and test biomedical imaging instruments. Although various types of solid tissue phantoms have been described in the literature, current phantom models are limited in that they do not have a depth feature that can be adjusted in real-time, they cannot be adapted to other applications, and their fabrication can be laborious and costly. Our goal was to develop an optical…

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Arcturus Phoon Promoted To Research Analyst
 823 1030 DaCosta Lab

We would like to congratulate Arcturus Phoon on his recent promotion to Clinical Research Analyst! His hard work and eagerness to take on responsibility is demonstrated every day, and helps propel the DaCosta Lab to new heights. We hope to see Mr. Phoon around the lab for years to come and wish him all the best in his new role!

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Antiviral treatment for treatment-naïve chronic hepatitis B: systematic review and network meta-analysis of randomized controlled trials
 150 150 DaCosta Lab

Wong, WWL; Pechivanoglou, P; Wong, J;  Bielecki, JM; Haines, A; Erman, A;  Saeed, YA; Phoon, A; Tadrous, M; Younis, M;  Rayad, NZ; Rac, V;  Janssen, HLA; Krahn, MD

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