COSTA LAB Translationally-Driven Molecular Imaging Molecular imaging has the potential to transform healthcare globally. D A

Research

We develop advanced molecular imaging solutions to improve diagnosis, treatment and monitoring of therapeutic response in cancer and other diseases.

Preclinical

Preclinical Research

The DaCosta research team develops new optical imaging tools, in the fields of intravital microscopy and molecular probes, which are used in specialized animal models of human cancers. These innovative tools enable us to visualize and quantify biological processes and therapy-induced changes in the living tumor. We capture a tumor’s dynamic microenvironment in vivo, over time, at single cell level producing award winning images.

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Clinical Research

The DaCosta lab is focused on bringing innovative solutions to clinical problems with the goal of improving patient care and outcomes. We rely on our clinical partners to frame the problems patients and clinicians experience today and look to offer effective, easily implementable solutions. The DaCosta lab is focused on developing diagnostic, treatment monitoring and guidance imaging tools for use in clinics and operating rooms.

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Clinical Trials

The DaCosta lab has completed over six PI-sponsored medical device clinical trials at UHN and collaborating centers across the Greater Toronto Area. From first-in-human prototype testing, to interventional device trials, our multidisciplinary team has extensive experience moving new devices from our translation research team through clinical testing across multiple indications with a focus on oncology and diabetic wound healing.

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Our Multidisciplinary

Team

Meet the Team
DaCosta Team photo

News

Dr. Ralph DaCosta joins UHN’s DORA Advisory Group
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In January, the Research Institutes at UHN signed the  San Francisco Declaration…

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DaCosta Lab presents at MBP’s Virtual Open House
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Even through a pandemic, the DaCosta Lab is always looking to recruit…

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Publications

Dr. Ralph DaCosta joins UHN’s DORA Advisory Group
672 378 DaCosta Lab

In January, the Research Institutes at UHN signed the  San Francisco Declaration…

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Engineering Functional Microvessels in Synthetic Polyurethane Random-Pore Scaffolds by Harnessing Perfusion Flow
1030 1019 DaCosta Lab

Wright ME, Yu JK, Jain D, Maeda A, Yeh SA, DaCosta R, Lin CP, Santerre JS; Biomaterials. 2020 Jun 23;256:120183
doi: 10.1016/j.biomaterials.2020.120183. Online ahead of print.

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Collaborations

Academic

Industry

Funding