Research

We develop advanced molecular imaging solutions to improve diagnosis, treatment and monitoring of therapeutic response in cancer and other diseases.

Preclinical

Preclinical Research

The DaCosta research team develops new optical imaging tools, in the fields of intravital microscopy and molecular probes, which are used in specialized animal models of human cancers. These innovative tools enable us to visualize and quantify biological processes and therapy-induced changes in the living tumor. We capture a tumor’s dynamic microenvironment in vivo, over time, at single cell level producing award winning images.

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Clinical Research

The DaCosta lab is focused on bringing innovative solutions to clinical problems with the goal of improving patient care and outcomes. We rely on our clinical partners to frame the problems patients and clinicians experience today and look to offer effective, easily implementable solutions. The DaCosta lab is focused on developing diagnostic, treatment monitoring and guidance imaging tools for use in clinics and operating rooms.

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Clinical Trials

The DaCosta lab has completed over six PI-sponsored medical device clinical trials at UHN and collaborating centers across the Greater Toronto Area. From first-in-human prototype testing, to interventional device trials, our multidisciplinary team has extensive experience moving new devices from our translation research team through clinical testing across multiple indications with a focus on oncology and diabetic wound healing.

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Our Multidisciplinary

Team

Meet the Team
DaCosta Team photo

News

Hot off the Press! Intraoperative Fluorescence Imaging with Aminolevulinic Acid Decets Grossly Occult Breast Cancer: A Phase II Randomized Controlled Trial is published in Breast Cancer Research
970 1030 DaCosta Lab

After a lengthy journey, our paper “Intraoperative fluorescence imaging with aminolevulinic acid…

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Welcome 2021 Summer Students!
1030 579 DaCosta Lab

We would like to welcome 5 high school and undergraduate summer students…

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Publications

Hot off the Press! Intraoperative Fluorescence Imaging with Aminolevulinic Acid Decets Grossly Occult Breast Cancer: A Phase II Randomized Controlled Trial is published in Breast Cancer Research
970 1030 DaCosta Lab

After a lengthy journey, our paper “Intraoperative fluorescence imaging with aminolevulinic acid…

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Dr. DaCosta participates in Annual 2021 MBP Career Symposium
806 579 DaCosta Lab

The annual MBP Symposium (which combines the James Lepock Memorial (JLM) Symposium…

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Collaborations

Academic

Industry

Funding