Ralph DaCosta

Dr. DaCosta to Deliver Keynote Presentation at St Michael’s 4th Annual Life Sciences Career Symposium
1000 500 DaCosta Lab

The St. Michael’s Hospital Research Student Association’s annual Life Sciences Career Symposium aims to connect trainees to distinguished experts in the Life Sciences. This year’s Symposium will take place on July 9th, 2021, featuring keynote speakers Dr. Samantha Yammine and Dr. Ralph DaCosta. Dr.DaCosta will headline the Biotechnology and Innovation session (1-3PM), sharing his experiences on his journey to becoming an academic scientist and entrepreneur in cancer imaging. Register here

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Dr. DaCosta participates in Annual 2021 MBP Career Symposium
806 579 DaCosta Lab

The annual MBP Symposium (which combines the James Lepock Memorial (JLM) Symposium and the annual MBP Alumni Night) is an important MBP event that provides an opportunity for MBP students to present their research in a conference setting. The MBP Symposium fosters scientific debate across disciplines, streams and institutes. MBP students have the opportunity to showcase their research in the form of either a scientific poster or oral presentation at the Symposium, and best presenters are recognized with merit awards. This event also featured keynote addresses from both local and international experts in the field of Medical Biophysics. This event…

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Intraoperative Fluorescence Imaging with Aminolevulinic Acid Detects Grossly Occult Breast Cancer: A Phase II Randomized Controlled Trial: Manuscript accepted to Breast Cancer Research
1030 606 DaCosta Lab

In 2009, the first patient was enrolled at Princess Margaret Cancer Center in this Phase II randomized controlled trial led by Dr. DaCosta in collaboration with surgeons Drs. Wey Leong and Alexandra Easson and pathologist Dr. Susan Done. The goal was to evaluate the clinical safety, feasibility and diagnostic performance of the PRODIGI handheld fluorescence imaging device combined with 5-ALA HCl for intraoperative visualization of invasive breast carcinomas. The Phase II trial was supported in large part by a $3M CIHR grant awarded to the DaCosta lab. Today, over a decade later, the manuscript for this study was accepted for…

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Dr. DaCosta discusses the origins of the lab and his serendipitous invention in UHN’s latest Behind the Breakthrough podcast episode
500 500 DaCosta Lab

Behind the Breakthrough, a podcast about the people behind the world-leading research at UHN, features Dr. Ralph DaCosta in Episode 7 of its second season. In this episode, Dr. DaCosta recollects his family’s immigration to Canada, his career path and serendipitous discovery that could revolutionize wound care. Hear about his groundbreaking work in visualizing cancer, his adventure becoming an inventor and entrepreneur, and how Terry Fox was the inspiration for his drive to enter cancer research.

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Dr. Ralph DaCosta joins UHN’s DORA Advisory Group
672 378 DaCosta Lab

In January, the Research Institutes at UHN signed the  San Francisco Declaration on Research Assessment (DORA), joining more than 1,500 institutions worldwide. DORA is a set of recommendations developed in 2012 by a group of editors and publishers of scholarly journals and is aimed at creating an improved and robust evaluation of the science and research impact of individuals and institutions. The UHN DORA Advisory Group was assembled to guide the implementation of these principles at the Research Institutes. This group is composed of a diverse group of PIs from across the seven UHN Research Institutes and will develop guidance…

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Engineering Functional Microvessels in Synthetic Polyurethane Random-Pore Scaffolds by Harnessing Perfusion Flow
1030 1019 DaCosta Lab

Wright ME, Yu JK, Jain D, Maeda A, Yeh SA, DaCosta R, Lin CP, Santerre JS; Biomaterials. 2020 Jun 23;256:120183
doi: 10.1016/j.biomaterials.2020.120183. Online ahead of print.

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Intraoperative Fluorescence Imaging with Aminolevulinic Acid Detects Grossly Occult Breast Cancer: a Phase II Randomized Controlled Trial (Conference Presentation)
838 680 DaCosta Lab

Ottolino-Perry K, Shahid A, DeLuca S, Son V, Liu Z, Rapic S, Thalanki Anantha NWang S, Chamma E, Blackmore K, Gibson C, Medeiros PJ, Majeed S, Chu A, Pizzolato A, Rosen CF, Lindvere-Teene L, Dunham D, Kulbatski I, Panzarella T, Done SJ, Easson AM, Leong WL, DaCosta RS; Proc. SPIE 11070, 17th International Photodynamic Association World Congress, 110701Y (14 August 2019)


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Intravital Imaging for Tracking of Angiogenesis and Cellular Events Around Surgical Bone Implants
1030 780 DaCosta Lab

Khosravi N, Mendes VC, Nirmal G, Majeed S, DaCosta R, Davies J; Tissue Eng Part C Methods. 2018 Nov;24(11):617-627
doi: 10.1089/ten.TEC.2018.0252

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A Feasibility Study of Photoacoustic Imaging of Ex Vivo Endoscopic Mucosal Resection Tissues from Barrett’s Esophagus Patients
800 557 DaCosta Lab

Lim L, Streutker CJ, Marcon N, Cirocco M, Lao A, Iakovlev VV, DaCosta R, Wilson BC; Endosc Int Open. 2017 Aug;5(8):E775-E783
doi: 10.1055/s-0043-111790

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