Search Results for “” – Page 2

New publications on the San Francisco Declaration on Research Assessment

There is a pressing need to improve the ways in which the outputs from scientific research is evaluated. To date, outputs from scientific research, which include research articles, intellectual property, and trained young scientists, are being evaluated based on Journal Impact Factor. The Journal Impact Factor is calculated by Thomson Reuters and was originally created as a tool to help…

Quantitative Intravital Imaging for Real-time Monitoring of Pancreatic Tumor Cell Hypoxia and Stroma in an Orthotopic Mouse Model

Our recent publication, “Quantitative Intravital Imaging for Real-time Monitoring of Pancreatic Tumor Cell Hypoxia and Stroma in an Orthotopic Mouse Model” was chosen to be the cover of Science Advances! Pancreatic cancer is a lethal disease with few successful treatment options. Recent evidence demonstrates that tumor hypoxia promotes pancreatic tumor invasion, metastasis, and therapy resistance. However, little is known about…

Dr. DaCosta and team present at the Image-Guided Therapeutics Symposium 2023

Dr. DaCosta presents an oral presentation and Shirley and Arcturus present a poster at the Image-Guided Therapeutics Symposium 2023. This scientific conference, held at Sunnybrook Health Sciences Centre, brings together scholars, students, academic, and industry researchers from the clinical and research communities to share the latest advances in the field of biomedical and diagnostic imaging, artificial intelligence, and image-guided therapeutics.…

Publications

All 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 Assessing the Accuracy of Bioluminescence Image-Guided Stereotactic Body Radiation Therapy of Orthotopic Pancreatic Tumors Using a Small Animal Irradiator https://dacostalab.ca/wp-content/uploads/2022/04/RadiationResearch1.png 983 970 DaCosta Lab DaCosta Lab https://dacostalab.ca/wp-content/uploads/2022/04/RadiationResearch1.png April 14, 2022 November 30, 2022 April 14, 2022 Our recent publication in Radiation Research, “Assessing the Accuracy…

DaCosta Lab publication on the cover of Science Advances!

We are excited to announce that our paper was chosen for the cover of Science Advances! The DaCosta Lab is pleased to announce that our recent publication, “Quantitative Intravital Imaging for Real-time Monitoring of Pancreatic Tumor Cell Hypoxia and Stroma in an Orthotopic Mouse Model” was chosen to be on the cover of Science Advances. Link to publication: https://www.science.org/doi/10.1126/sciadv.ade8672 Authors: Dr.…

Exploring the merits of research performance measures that comply with the San Francisco Declaration on Research Assessment and strategies to overcome barriers of adoption: qualitative interviews with administrators and researchers

An advisory group at UHN applied an evidence- and consensus-based process to derive measures from published research, and national and international best practices, then engaged researchers and research leaders across all of the institutes through a two-round Delphi survey. This approach identified measures that reflect the relevance of the research program, funding, innovative outputs, publications, collaboration, recognition, and challenges to…

Dr. Timothy Samuel successfully defends his PhD!

The DaCosta Lab congratulates Dr. Timothy Samuel for successfully defending his PhD on May 2, 2023! His PhD thesis, entitled “In Vivo Effects of Stereotactic Body Radiation Therapy on the Pancreatic Tumor Microenvironment,” focuses on improving our understanding of how different elements of the pancreatic tumor microenvironment (e.g., tumor cells, blood vessels, oxygenation and collagen structures) respond to high-dose radiotherapy.…

DORA-compliant measures of research quality and impact to assess the performance of researchers in biomedical institutions: Review of published research, international best practice and Delphi survey

Shortly before the pandemic, the research institutes at UHN signed the San Francisco Declaration on Research Assessment (DORA)—a set of principles aimed at enhancing and modernizing research assessment. DORA promotes the evaluation of the quality and impact of research, and the elimination of using journal-based metrics (e.g., Journal Impact Factor) for decisions related to hiring, appointment, annual review, and promotion. An…

Dr. Shirley Wang is promoted to CRCII!

Dr. Shirley Wang has been promoted to Clinical Research Coordinator II. Dr. Wang has worked in the DaCosta lab since 2018, managing several clinical trials, namely the FLIGHT Phase IV trial, the ALA Breast Cancer Phase III trial, and the Wound Area Reduction trial. She has been responsible for ensuring project milestones are met, initiating new clinical trials, directly supervising…

Dr. Elyse Digby successfully defends her PhD!

Dr. Elyse Digby successfully defended her PhD thesis on April 4, 2023! Her PhD research project focused on applying novel small molecule photosensitizers to improve the efficacy of PDT. She studied the design of photosensitizers that would be selectively activated in cancers overexpressing certain enzyme targets (e.g.., human NAD(P)H quinone oxidoreductase 1), a photosensitizer that was able to directly target and…